Decipher Prostate Genomic Classifier

Decipher Prostate provides clinicians and patients with genomic insights to help make more informed prostate cancer treatment decisions.

For Providers For Patients
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What is the Decipher Prostate test?

Decipher Prostate is a tissue-based molecular test used to assess risk of metastasis or metastatic progression in patients with localized or advanced prostate cancer.

It is the only gene expression test available and covered by Medicare to inform treatment decisions for patients across the continuum of prostate cancer.

Inherited Risk Assessment
Screening and Risk Assessment
Diagnosis
Prognosis
Treatment Guidance
Recurrence Monitoring

Focused on evidence-driven science

Most widely-published gene expression test for prostate cancer1

>300K

Patients tested to date2

>115

Publications demonstrating the clinical validity and utility of Decipher Prostate3

>25

Ongoing prospective randomized clinical trials that include Decipher Prostate

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Access our Decipher portals

Decipher provider ordering portal

Order Decipher Prostate test and view reports.

Have questions about the ordering process? Contact us today.

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Decipher patient payment portal

Pay your Decipher Prostate bill using our secure online portal.

Have questions about your bill or payment? Contact us today.

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Patient Story

A urologist’s personal Decipher journey

Urologist Dr. Arnold Bullock, from the Washington University School of Medicine, shares his very personal story of being diagnosed with prostate cancer and using the Decipher Prostate test in his clinical practice for his patients.

Watch Dr. Bullock’s conversation with his urologist and former colleague, Dr. Eric Kim, Chief of Urology at the University of Nevada Reno School of Medicine, Renown Medical Group.

Selecting a prostate cancer management strategy is a nuanced process, balancing the oncologic benefits of treatments with their impacts on quality of life. The Decipher Prostate test helps us as providers to make sure the right patients are getting the right treatment at the right time.”3

Ashley E. Ross, M.D., Ph.D. Associate Professor of Urology and Clinical Director for the Polsky Urological Oncology Center Northwestern Feinberg School of Medicine

The prostate cancer landscape

Statistics

Prostate cancer is the most commonly diagnosed cancer in men in the United States. 

  • >333K men are expected to be diagnosed with prostate cancer in the US in 2026.4
  • >36K men are expected to die of prostate cancer in the US in 2026.4
  • 1 in 8 men are expected to be diagnosed with prostate cancer in their lifetime.4
  • New prostate cancer cases are expected to double worldwide between 2020 to 2040.5

Challenges

Prostate cancer does not behave the same way in every person.

Some tumors grow very slowly, while others are aggressive and can spread quickly.

Understanding each patient’s unique risk is key to choosing the right treatment.

Relying only on clinical and pathological factors for risk assessment and treatment selection does not always reflect the tumor’s underlying biology, which can result in over- or under-treatment.

Our Approach

Decipher Prostate helps guide personalized care decisions

Decipher Prostate provides clinicians and patients with actionable biological insights that complement clinical factors to help enable more personalized treatment decisions.

Take the next step and learn more about Decipher Prostate.

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References

  1. Based on data available from commercial websites as of February 17, 2026.
  2. Decipher patients tested from inception through December 31, 2025.
  3. Company data on file as of February 17, 2026.
  4. American Cancer Society. Cancer Facts & Figures. 2026. Atlanta, GA: American Cancer Society; 2026. Accessed February 12, 2026. https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2026/2026-cancer-facts-and-figures.pdf
  5. James ND, et al. Lancet Oncol. 2024. DOI: 10.1016/s0140-6736(24)00651-2

Disclaimers

Decipher testing is available in the United States as part of Veracyte’s CLIA-validated laboratory developed test (LDT) service, and FDA clearance is not required.

Talk to your doctor about whether Veracyte tests might be right for you.